Consistency of Laboratory Monitoring During Initiation of Mineralocorticoid Receptor Antagonist Therapy in Patients With Heart Failure.
نویسندگان
چکیده
Consistency of LaboratoryMonitoring During Initiation ofMineralocorticoid Receptor Antagonist Therapy in PatientsWithHeart Failure Mineralocorticoid receptor antagonists (MRAs) are a cornerstone of heart failure therapy but have a risk of hyperkalemia. Clinical guidelines recommend close monitoring of renal function and electrolyte levels throughout the course of therapy.1 No large studies have examinedwhether laboratory monitoring occurs routinely in community practice.
منابع مشابه
Characterization of Mineralocorticoid Receptor Antagonist Therapy Initiation in High-Risk Patients With Heart Failure
Based on the results of pivotal clinical trials showing significant reductions in mortality and morbidity in patients with mild to severe symptoms of heart failure, guidelines recommend mineralocorticoid receptor antagonist (MRA) therapy for patients with reduced left ventricular ejection fraction of ≤35% and New York Heart Association class II to IV heart failure symptoms in the absence of con...
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BACKGROUND Heart failure guidelines recommend routine monitoring of serum potassium, and renal function in patients treated with a mineralocorticoid receptor antagonist (MRA). How these recommendations are implemented in high-risk patients or according to setting of drug initiation is poorly characterized. METHODS AND RESULTS We conducted a retrospective cohort study of Medicare beneficiaries...
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BACKGROUND Mineralocorticoid receptor antagonists (MRA) reduce morbidity and mortality in heart failure with reduced ejection fraction but can cause hyperkalemia and acute kidney injury. Guidelines recommend measurement of serum potassium (K) and creatinine (Cr) before and serially after MRA initiation, but the extent to which this occurs is unknown. METHODS AND RESULTS Using electronic data ...
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ورودعنوان ژورنال:
- JAMA
دوره 314 18 شماره
صفحات -
تاریخ انتشار 2015